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Multivariate extension of penalized regression on summary statistics to construct polygenic risk scores for correlated traits

Genetic correlations between human traits and disorders such as schizophrenia (SZ) and bipolar disorder (BD) diagnoses are well established. Improved prediction of individual traits has been obtained by combining predictors of multiple genetically correlated traits derived from summary statistics pr...

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Detalles Bibliográficos
Autores principales:	Bahda, Meriem, Ricard, Jasmin, Girard, Simon L., Maziade, Michel, Isabelle, Maripier, Bureau, Alexandre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276147/ https://www.ncbi.nlm.nih.gov/pubmed/37333772 http://dx.doi.org/10.1016/j.xhgg.2023.100209

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