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Development of the nonreceptor tyrosine kinase FER-targeting PROTACs as a potential strategy for antagonizing ovarian cancer cell motility and invasiveness

Aberrant overexpression of nonreceptor tyrosine kinase FER (Fps/Fes Related) has been reported in various ovarian carcinoma–derived tumor cells and is a poor prognosis factor for patient survival. It plays an essential role in tumor cell migration and invasion, acting concurrently in both kinase-dep...

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Detalles Bibliográficos
Autores principales:	Zhang, Yanchun, Xiong, Xuexue, Sun, Renhong, Zhu, Xiaotong, Wang, Chen, Jiang, Biao, Yang, Xiaobao, Li, Dake, Fan, Gaofeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276154/ https://www.ncbi.nlm.nih.gov/pubmed/37196766 http://dx.doi.org/10.1016/j.jbc.2023.104825

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