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A successfully treated gastric mucormycosis in an immunocompetent patient: Case report and literature review
Mucormycosis is an opportunistic fungal infection that usually affects patients with diabetes mellitus or immunosuppression. The fungus invades the nearby blood vessels leading to thrombosis and necrosis of the organs involved. Although Mucorales can invade any organ in the body, the gastrointestina...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276240/ https://www.ncbi.nlm.nih.gov/pubmed/37334344 http://dx.doi.org/10.1002/ccr3.7540 |
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author | Albtoosh, Asma Salameh Shaf'ei, Moayad Al Hayek, Sa'ed Ramdan, Lara Ibrahim Abu Shahin, Nisreen Alzyoud, Mohammad Farah, Randa |
author_facet | Albtoosh, Asma Salameh Shaf'ei, Moayad Al Hayek, Sa'ed Ramdan, Lara Ibrahim Abu Shahin, Nisreen Alzyoud, Mohammad Farah, Randa |
author_sort | Albtoosh, Asma Salameh |
collection | PubMed |
description | Mucormycosis is an opportunistic fungal infection that usually affects patients with diabetes mellitus or immunosuppression. The fungus invades the nearby blood vessels leading to thrombosis and necrosis of the organs involved. Although Mucorales can invade any organ in the body, the gastrointestinal system is an uncommon site for infection. Mucormycosis is a fatal infection, and prompt intervention is required to ensure survival. In this report, we present a case of a 46‐year‐old man with history of valve replacement surgery on warfarin, who admitted with abdominal pain and life‐threatening gastrointestinal bleeding. Esophagogastroduodenoscopy revealed an active gastric ulcer bleeding, and the diagnosis of mucormycosis infection was confirmed with direct microscopy and histopathological evaluation from a tissue biopsy. Typically, antifungal therapy alone is inadequate to control mucormycosis infection and surgical intervention is often required. Our patient was successfully treated using antifungal therapy alone. This report presents a rare case of gastrointestinal mucormycosis in setting of valve replacement and was successfully treated with antifungal therapy. |
format | Online Article Text |
id | pubmed-10276240 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-102762402023-06-18 A successfully treated gastric mucormycosis in an immunocompetent patient: Case report and literature review Albtoosh, Asma Salameh Shaf'ei, Moayad Al Hayek, Sa'ed Ramdan, Lara Ibrahim Abu Shahin, Nisreen Alzyoud, Mohammad Farah, Randa Clin Case Rep Case Report Mucormycosis is an opportunistic fungal infection that usually affects patients with diabetes mellitus or immunosuppression. The fungus invades the nearby blood vessels leading to thrombosis and necrosis of the organs involved. Although Mucorales can invade any organ in the body, the gastrointestinal system is an uncommon site for infection. Mucormycosis is a fatal infection, and prompt intervention is required to ensure survival. In this report, we present a case of a 46‐year‐old man with history of valve replacement surgery on warfarin, who admitted with abdominal pain and life‐threatening gastrointestinal bleeding. Esophagogastroduodenoscopy revealed an active gastric ulcer bleeding, and the diagnosis of mucormycosis infection was confirmed with direct microscopy and histopathological evaluation from a tissue biopsy. Typically, antifungal therapy alone is inadequate to control mucormycosis infection and surgical intervention is often required. Our patient was successfully treated using antifungal therapy alone. This report presents a rare case of gastrointestinal mucormycosis in setting of valve replacement and was successfully treated with antifungal therapy. John Wiley and Sons Inc. 2023-06-17 /pmc/articles/PMC10276240/ /pubmed/37334344 http://dx.doi.org/10.1002/ccr3.7540 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Albtoosh, Asma Salameh Shaf'ei, Moayad Al Hayek, Sa'ed Ramdan, Lara Ibrahim Abu Shahin, Nisreen Alzyoud, Mohammad Farah, Randa A successfully treated gastric mucormycosis in an immunocompetent patient: Case report and literature review |
title | A successfully treated gastric mucormycosis in an immunocompetent patient: Case report and literature review |
title_full | A successfully treated gastric mucormycosis in an immunocompetent patient: Case report and literature review |
title_fullStr | A successfully treated gastric mucormycosis in an immunocompetent patient: Case report and literature review |
title_full_unstemmed | A successfully treated gastric mucormycosis in an immunocompetent patient: Case report and literature review |
title_short | A successfully treated gastric mucormycosis in an immunocompetent patient: Case report and literature review |
title_sort | successfully treated gastric mucormycosis in an immunocompetent patient: case report and literature review |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276240/ https://www.ncbi.nlm.nih.gov/pubmed/37334344 http://dx.doi.org/10.1002/ccr3.7540 |
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