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Electrochemical Biosensor for the Detection of SARS-CoV-2 Main Protease and Its Inhibitor Ebselen

This work reported an electrochemical method for the detection of SARS-CoV-2 major protease (Mpro). Specifically, ferrocene (Fc)-labeled peptide substrates were immobilized on the gold nanoparticles (AuNPs)-modified electrode. Cleavage of the peptides by Mpro led to the release of Fc tags and the de...

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Detalles Bibliográficos
Autores principales: Zhang, Qiongyu, Liu, Gang, Ou, Lingbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by ESG. Published by Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276345/
https://www.ncbi.nlm.nih.gov/pubmed/37359208
http://dx.doi.org/10.20964/2022.04.19