Biological roles of A-to-I editing: implications in innate immunity, cell death, and cancer immunotherapy

Adenosine-to-inosine (A-to-I) editing, a key RNA modification widely found in eukaryotes, is catalyzed by adenosine deaminases acting on RNA (ADARs). Such RNA editing destabilizes endogenous dsRNAs, which are subsequently recognized by the sensors of innate immune and other proteins as autologous ds...

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Detalles Bibliográficos
Autores principales: Yuan, Jing, Xu, Li, Bao, Hai-Juan, Wang, Jie-lin, Zhao, Yang, Chen, Shuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276482/
https://www.ncbi.nlm.nih.gov/pubmed/37328893
http://dx.doi.org/10.1186/s13046-023-02727-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276482/
https://www.ncbi.nlm.nih.gov/pubmed/37328893
http://dx.doi.org/10.1186/s13046-023-02727-9

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