Nrf2 protects against myocardial ischemia-reperfusion injury in diabetic rats by inhibiting Drp1-mediated mitochondrial fission

Mitochondrial dysfunction and oxidative stress are considered to be two main drivers of diabetic myocardial ischemia-reperfusion injury (DM + MIRI). Nuclear factor-erythroid 2-related factor 2 (Nrf2) and Dynamin-related protein 1 (Drp1) play central roles in maintaining mitochondrial homeostasis and...

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Detalles Bibliográficos
Autores principales: Wang, Xiao-Li, Zhu, Qian-Qian, Simayi, Alimujiang, Xu, Gui-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276614/
https://www.ncbi.nlm.nih.gov/pubmed/37333454
http://dx.doi.org/10.1515/med-2023-0711

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