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The NAD salvage pathway in mesenchymal cells is indispensable for skeletal development in mice
NAD is an essential co-factor for cellular energy metabolism and multiple other processes. Systemic NAD(+) deficiency has been implicated in skeletal deformities during development in both humans and mice. NAD levels are maintained by multiple synthetic pathways but which ones are important in bone...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276814/ https://www.ncbi.nlm.nih.gov/pubmed/37330524 http://dx.doi.org/10.1038/s41467-023-39392-7 |