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The NAD salvage pathway in mesenchymal cells is indispensable for skeletal development in mice

NAD is an essential co-factor for cellular energy metabolism and multiple other processes. Systemic NAD(+) deficiency has been implicated in skeletal deformities during development in both humans and mice. NAD levels are maintained by multiple synthetic pathways but which ones are important in bone...

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Detalles Bibliográficos
Autores principales:	Warren, Aaron, Porter, Ryan M., Reyes-Castro, Olivia, Ali, Md Mohsin, Marques-Carvalho, Adriana, Kim, Ha-Neui, Gatrell, Landon B., Schipani, Ernestina, Nookaew, Intawat, O’Brien, Charles A., Morello, Roy, Almeida, Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276814/ https://www.ncbi.nlm.nih.gov/pubmed/37330524 http://dx.doi.org/10.1038/s41467-023-39392-7

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