Exploration of the optimal GS-441524 trough concentration for treating COVID-19

OBJECTIVES: Remdesivir (RDV) is the cornerstone for treating coronavirus disease 2019 (COVID-19). The active metabolite of RDV, GS-441524 (a nucleoside analog), has high inter-individual variability in plasma concentration; however, its concentration-response relationship is still unclear. This stud...

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Detalles Bibliográficos
Autores principales: Nakano, Yuki, Inokuchi, Yoko, Hayama, Tadashi, Hirai, Toshinori, Nishiyama, Mamoru, Sueyasu, Yoshiko, Yokoo, Kenjo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd and International Society of Antimicrobial Chemotherapy. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276898/
https://www.ncbi.nlm.nih.gov/pubmed/37339712
http://dx.doi.org/10.1016/j.ijantimicag.2023.106892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276898/
https://www.ncbi.nlm.nih.gov/pubmed/37339712
http://dx.doi.org/10.1016/j.ijantimicag.2023.106892

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