Astrocytic uptake of neuronal corpses promotes cell-to-cell spreading of tau pathology

Tau deposits in astrocytes are frequently found in Alzheimer’s disease (AD) and other tauopathies. Since astrocytes do not express tau, the inclusions have been suggested to be of neuronal origin. However, the mechanisms behind their appearance and their relevance for disease progression remain unkn...

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Detalles Bibliográficos
Autores principales: Mothes, Tobias, Portal, Benjamin, Konstantinidis, Evangelos, Eltom, Khalid, Libard, Sylwia, Streubel-Gallasch, Linn, Ingelsson, Martin, Rostami, Jinar, Lindskog, Maria, Erlandsson, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276914/
https://www.ncbi.nlm.nih.gov/pubmed/37330529
http://dx.doi.org/10.1186/s40478-023-01589-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276914/
https://www.ncbi.nlm.nih.gov/pubmed/37330529
http://dx.doi.org/10.1186/s40478-023-01589-8

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