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Invasive Acantholytic Ocular Surface Squamous Neoplasia: A Rare Case
Ocular surface squamous neoplasia (OSSN) is a spectrum of intraepithelial and invasive neoplastic lesions of the conjunctiva and cornea. OSSN is a rare but potentially sight-threatening ocular malignancy that can be challenging to diagnose due to its clinical and histopathological resemblance to ben...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276922/ https://www.ncbi.nlm.nih.gov/pubmed/37337502 http://dx.doi.org/10.7759/cureus.39219 |
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author | Sharma, Avi Daigavane, Sachin Bhake, Arvind |
author_facet | Sharma, Avi Daigavane, Sachin Bhake, Arvind |
author_sort | Sharma, Avi |
collection | PubMed |
description | Ocular surface squamous neoplasia (OSSN) is a spectrum of intraepithelial and invasive neoplastic lesions of the conjunctiva and cornea. OSSN is a rare but potentially sight-threatening ocular malignancy that can be challenging to diagnose due to its clinical and histopathological resemblance to benign ocular surface lesions. However, OSSN can lead to significant ocular and systemic morbidity, including vision loss and metastasis. Various risk factors have been identified, including ultraviolet radiation exposure, human papillomavirus infection, and immunosuppression. The histopathological analysis of the lesion is of utmost importance in diagnosing and further managing squamous cell carcinoma. The acantholytic variant of squamous cell carcinoma is uncommon. Here, we present the case of a 69-year-old male who presented with an invasive mass of progressive growth on the left eyeball extending into the visual axis. The patient underwent extended enucleation, and a histopathological analysis demonstrated a rare acantholytic variant of squamous cell carcinoma. |
format | Online Article Text |
id | pubmed-10276922 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-102769222023-06-19 Invasive Acantholytic Ocular Surface Squamous Neoplasia: A Rare Case Sharma, Avi Daigavane, Sachin Bhake, Arvind Cureus Ophthalmology Ocular surface squamous neoplasia (OSSN) is a spectrum of intraepithelial and invasive neoplastic lesions of the conjunctiva and cornea. OSSN is a rare but potentially sight-threatening ocular malignancy that can be challenging to diagnose due to its clinical and histopathological resemblance to benign ocular surface lesions. However, OSSN can lead to significant ocular and systemic morbidity, including vision loss and metastasis. Various risk factors have been identified, including ultraviolet radiation exposure, human papillomavirus infection, and immunosuppression. The histopathological analysis of the lesion is of utmost importance in diagnosing and further managing squamous cell carcinoma. The acantholytic variant of squamous cell carcinoma is uncommon. Here, we present the case of a 69-year-old male who presented with an invasive mass of progressive growth on the left eyeball extending into the visual axis. The patient underwent extended enucleation, and a histopathological analysis demonstrated a rare acantholytic variant of squamous cell carcinoma. Cureus 2023-05-19 /pmc/articles/PMC10276922/ /pubmed/37337502 http://dx.doi.org/10.7759/cureus.39219 Text en Copyright © 2023, Sharma et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Ophthalmology Sharma, Avi Daigavane, Sachin Bhake, Arvind Invasive Acantholytic Ocular Surface Squamous Neoplasia: A Rare Case |
title | Invasive Acantholytic Ocular Surface Squamous Neoplasia: A Rare Case |
title_full | Invasive Acantholytic Ocular Surface Squamous Neoplasia: A Rare Case |
title_fullStr | Invasive Acantholytic Ocular Surface Squamous Neoplasia: A Rare Case |
title_full_unstemmed | Invasive Acantholytic Ocular Surface Squamous Neoplasia: A Rare Case |
title_short | Invasive Acantholytic Ocular Surface Squamous Neoplasia: A Rare Case |
title_sort | invasive acantholytic ocular surface squamous neoplasia: a rare case |
topic | Ophthalmology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276922/ https://www.ncbi.nlm.nih.gov/pubmed/37337502 http://dx.doi.org/10.7759/cureus.39219 |
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