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Association between 6-thioguanine nucleotide levels and preventing production of antibodies to infliximab in patients with inflammatory bowel disease

OBJECTIVE: Combination therapy with infliximab and a thiopurine has been shown to be more effective than monotherapy in patients with inflammatory bowel disease (IBD). The therapeutic efficacy of thiopurines is correlated with 6-thioguanine (6-TGN) levels between 235 and 450 pmol/8×10(8) erythrocyte...

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Detalles Bibliográficos
Autores principales:	Phillips, Jennifer, Leary, Sam, Tyrrell-Price, Jonathan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Inflammatory Bowel Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277032/ https://www.ncbi.nlm.nih.gov/pubmed/37328288 http://dx.doi.org/10.1136/bmjgast-2023-001149

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