A Plaque-Like CD34-Positive Dermal Fibroma Presenting as an Acquired Papule

CD34-positive dermal fibromas (PDFs) are cutaneous neoplasms that display a characteristic pattern of superficial dermal spindle cell proliferation on histopathology evaluation. They are clinically heterogenous in presentation and thought to follow a benign course. CD34-PDFs have features that overl...

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Detalles Bibliográficos
Autores principales: Kanji, Alpa, Carton, James, Hewitt, Caroline, Phillips, Derrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Dermatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277152/
https://www.ncbi.nlm.nih.gov/pubmed/37337490
http://dx.doi.org/10.7759/cureus.39231
Descripción
Sumario:CD34-positive dermal fibromas (PDFs) are cutaneous neoplasms that display a characteristic pattern of superficial dermal spindle cell proliferation on histopathology evaluation. They are clinically heterogenous in presentation and thought to follow a benign course. CD34-PDFs have features that overlap with dermatofibrosarcoma protuberans (DFSP), a locally aggressive low-grade superficial sarcoma. Cytogenetic studies are essential to distinguish the two. This report presents the case of a 38-year-old female with a CD34-PDF on the right antecubital fossa.

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