A Plaque-Like CD34-Positive Dermal Fibroma Presenting as an Acquired Papule

CD34-positive dermal fibromas (PDFs) are cutaneous neoplasms that display a characteristic pattern of superficial dermal spindle cell proliferation on histopathology evaluation. They are clinically heterogenous in presentation and thought to follow a benign course. CD34-PDFs have features that overl...

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Detalles Bibliográficos
Autores principales: Kanji, Alpa, Carton, James, Hewitt, Caroline, Phillips, Derrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Dermatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277152/
https://www.ncbi.nlm.nih.gov/pubmed/37337490
http://dx.doi.org/10.7759/cureus.39231
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author Kanji, Alpa
Carton, James
Hewitt, Caroline
Phillips, Derrick
author_facet Kanji, Alpa
Carton, James
Hewitt, Caroline
Phillips, Derrick
author_sort Kanji, Alpa
collection PubMed
description CD34-positive dermal fibromas (PDFs) are cutaneous neoplasms that display a characteristic pattern of superficial dermal spindle cell proliferation on histopathology evaluation. They are clinically heterogenous in presentation and thought to follow a benign course. CD34-PDFs have features that overlap with dermatofibrosarcoma protuberans (DFSP), a locally aggressive low-grade superficial sarcoma. Cytogenetic studies are essential to distinguish the two. This report presents the case of a 38-year-old female with a CD34-PDF on the right antecubital fossa.
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spelling pubmed-102771522023-06-19 A Plaque-Like CD34-Positive Dermal Fibroma Presenting as an Acquired Papule Kanji, Alpa Carton, James Hewitt, Caroline Phillips, Derrick Cureus Dermatology CD34-positive dermal fibromas (PDFs) are cutaneous neoplasms that display a characteristic pattern of superficial dermal spindle cell proliferation on histopathology evaluation. They are clinically heterogenous in presentation and thought to follow a benign course. CD34-PDFs have features that overlap with dermatofibrosarcoma protuberans (DFSP), a locally aggressive low-grade superficial sarcoma. Cytogenetic studies are essential to distinguish the two. This report presents the case of a 38-year-old female with a CD34-PDF on the right antecubital fossa. Cureus 2023-05-19 /pmc/articles/PMC10277152/ /pubmed/37337490 http://dx.doi.org/10.7759/cureus.39231 Text en Copyright © 2023, Kanji et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Kanji, Alpa
Carton, James
Hewitt, Caroline
Phillips, Derrick
A Plaque-Like CD34-Positive Dermal Fibroma Presenting as an Acquired Papule
title A Plaque-Like CD34-Positive Dermal Fibroma Presenting as an Acquired Papule
title_full A Plaque-Like CD34-Positive Dermal Fibroma Presenting as an Acquired Papule
title_fullStr A Plaque-Like CD34-Positive Dermal Fibroma Presenting as an Acquired Papule
title_full_unstemmed A Plaque-Like CD34-Positive Dermal Fibroma Presenting as an Acquired Papule
title_short A Plaque-Like CD34-Positive Dermal Fibroma Presenting as an Acquired Papule
title_sort plaque-like cd34-positive dermal fibroma presenting as an acquired papule
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277152/
https://www.ncbi.nlm.nih.gov/pubmed/37337490
http://dx.doi.org/10.7759/cureus.39231
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