High-throughput functional analysis of autism genes in zebrafish identifies convergence in dopaminergic and neuroimmune pathways

Advancing from gene discovery in autism spectrum disorders (ASDs) to the identification of biologically relevant mechanisms remains a central challenge. Here, we perform parallel in vivo functional analysis of 10 ASD genes at the behavioral, structural, and circuit levels in zebrafish mutants, revea...

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Detalles Bibliográficos
Autores principales: Weinschutz Mendes, Hellen, Neelakantan, Uma, Liu, Yunqing, Fitzpatrick, Sarah E., Chen, Tianying, Wu, Weimiao, Pruitt, April, Jin, David S., Jamadagni, Priyanka, Carlson, Marina, Lacadie, Cheryl M., Enriquez, Kristen D., Li, Ningshan, Zhao, Dejian, Ijaz, Sundas, Sakai, Catalina, Szi, Christina, Rooney, Brendan, Ghosh, Marcus, Nwabudike, Ijeoma, Gorodezky, Andrea, Chowdhury, Sumedha, Zaheer, Meeraal, McLaughlin, Sarah, Fernandez, Joseph M., Wu, Jia, Eilbott, Jeffrey A., Wyk, Brent Vander, Rihel, Jason, Papademetris, Xenophon, Wang, Zuoheng, Hoffman, Ellen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277173/
https://www.ncbi.nlm.nih.gov/pubmed/36933215
http://dx.doi.org/10.1016/j.celrep.2023.112243

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