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Coronavirus disease 2019 and vitamin D

Vitamin D deficiency is one of the most common vitamin deficiencies across different populations. It has primarily been implicated in the development of metabolic bone disease in adults and children. However, in recent years its role in immunomodulation has also emerged and has gained further import...

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Detalles Bibliográficos
Autores principales: Kapoor, Nitin, Kalra, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277257/
https://www.ncbi.nlm.nih.gov/pubmed/37394290
http://dx.doi.org/10.1016/j.beem.2023.101791
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author Kapoor, Nitin
Kalra, Sanjay
author_facet Kapoor, Nitin
Kalra, Sanjay
author_sort Kapoor, Nitin
collection PubMed
description Vitamin D deficiency is one of the most common vitamin deficiencies across different populations. It has primarily been implicated in the development of metabolic bone disease in adults and children. However, in recent years its role in immunomodulation has also emerged and has gained further importance since the occurrence of coronavirus disease 2019 (COVID-19). Here, we describe the most recent literature on vitamin D and its impact on immunomodulatory pathways. Furthermore, the current evidence on the impact of vitamin D deficiency on COVID-19 infection, severity, and prognosis is summarised. We also highlight the key research gaps in this field that need further research.
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spelling pubmed-102772572023-06-21 Coronavirus disease 2019 and vitamin D Kapoor, Nitin Kalra, Sanjay Best Pract Res Clin Endocrinol Metab Article Vitamin D deficiency is one of the most common vitamin deficiencies across different populations. It has primarily been implicated in the development of metabolic bone disease in adults and children. However, in recent years its role in immunomodulation has also emerged and has gained further importance since the occurrence of coronavirus disease 2019 (COVID-19). Here, we describe the most recent literature on vitamin D and its impact on immunomodulatory pathways. Furthermore, the current evidence on the impact of vitamin D deficiency on COVID-19 infection, severity, and prognosis is summarised. We also highlight the key research gaps in this field that need further research. Elsevier Ltd. 2023-06-19 /pmc/articles/PMC10277257/ /pubmed/37394290 http://dx.doi.org/10.1016/j.beem.2023.101791 Text en © 2023 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Kapoor, Nitin
Kalra, Sanjay
Coronavirus disease 2019 and vitamin D
title Coronavirus disease 2019 and vitamin D
title_full Coronavirus disease 2019 and vitamin D
title_fullStr Coronavirus disease 2019 and vitamin D
title_full_unstemmed Coronavirus disease 2019 and vitamin D
title_short Coronavirus disease 2019 and vitamin D
title_sort coronavirus disease 2019 and vitamin d
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277257/
https://www.ncbi.nlm.nih.gov/pubmed/37394290
http://dx.doi.org/10.1016/j.beem.2023.101791
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