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Implementation of a massive transfusion protocol: A single trauma center experience from South Korea
BACKGROUND: Massive transfusion (MT) is traditionally defined as transfusion of more than 10 units of red blood cells (RBCs) within the first 24 h after admission. The aim of this study is to analyze the trend of MT in regional trauma center including ratio of fresh frozen plasma (FFP) and packed RB...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Kare Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277374/ https://www.ncbi.nlm.nih.gov/pubmed/36169455 http://dx.doi.org/10.14744/tjtes.2021.07824 |
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author | Lee, Min A Park, HyeMin Yu, Byungchul Choi, Kang Kook Park, Youngeun Lee, Gil Jae |
author_facet | Lee, Min A Park, HyeMin Yu, Byungchul Choi, Kang Kook Park, Youngeun Lee, Gil Jae |
author_sort | Lee, Min A |
collection | PubMed |
description | BACKGROUND: Massive transfusion (MT) is traditionally defined as transfusion of more than 10 units of red blood cells (RBCs) within the first 24 h after admission. The aim of this study is to analyze the trend of MT in regional trauma center including ratio of fresh frozen plasma (FFP) and packed RBC. METHODS: Retrospective data were driven from 2014 to 2016. A total of 185 patients who received more than 10 packed RBC units within the first 24 h after admission were included in the study. We analyzed transfusion requirements for each time interval 4 h and 24 h after admission. Moreover, we compared transfusion characteristics between survival and non-survival group, between high FFP:RBC group (≥1: 2) and low FFP:RBC group (<1: 2), and between the first half and latter half period. RESULTS: There was a trend for improvement in the FFP:RBC ratio after applying the MT protocol. The FFP:RBC ratio increased from 1:1.7 to 1:1.4 within 24 h after arrival. The time to first transfusion was shortened (137–106 min). Mortality was lower in high FFP:RBC group than that of low FFP:RBC group. CONCLUSION: In our study, the MT protocol improved the FFP:RBC ratio. A higher FFP:RBC ratio also led to an improvement in the mortality rate in MT patients. |
format | Online Article Text |
id | pubmed-10277374 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Kare Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-102773742023-06-20 Implementation of a massive transfusion protocol: A single trauma center experience from South Korea Lee, Min A Park, HyeMin Yu, Byungchul Choi, Kang Kook Park, Youngeun Lee, Gil Jae Ulus Travma Acil Cerrahi Derg Original Article BACKGROUND: Massive transfusion (MT) is traditionally defined as transfusion of more than 10 units of red blood cells (RBCs) within the first 24 h after admission. The aim of this study is to analyze the trend of MT in regional trauma center including ratio of fresh frozen plasma (FFP) and packed RBC. METHODS: Retrospective data were driven from 2014 to 2016. A total of 185 patients who received more than 10 packed RBC units within the first 24 h after admission were included in the study. We analyzed transfusion requirements for each time interval 4 h and 24 h after admission. Moreover, we compared transfusion characteristics between survival and non-survival group, between high FFP:RBC group (≥1: 2) and low FFP:RBC group (<1: 2), and between the first half and latter half period. RESULTS: There was a trend for improvement in the FFP:RBC ratio after applying the MT protocol. The FFP:RBC ratio increased from 1:1.7 to 1:1.4 within 24 h after arrival. The time to first transfusion was shortened (137–106 min). Mortality was lower in high FFP:RBC group than that of low FFP:RBC group. CONCLUSION: In our study, the MT protocol improved the FFP:RBC ratio. A higher FFP:RBC ratio also led to an improvement in the mortality rate in MT patients. Kare Publishing 2022-10-03 /pmc/articles/PMC10277374/ /pubmed/36169455 http://dx.doi.org/10.14744/tjtes.2021.07824 Text en Copyright © 2022 Turkish Journal of Trauma and Emergency Surgery https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License |
spellingShingle | Original Article Lee, Min A Park, HyeMin Yu, Byungchul Choi, Kang Kook Park, Youngeun Lee, Gil Jae Implementation of a massive transfusion protocol: A single trauma center experience from South Korea |
title | Implementation of a massive transfusion protocol: A single trauma center experience from South Korea |
title_full | Implementation of a massive transfusion protocol: A single trauma center experience from South Korea |
title_fullStr | Implementation of a massive transfusion protocol: A single trauma center experience from South Korea |
title_full_unstemmed | Implementation of a massive transfusion protocol: A single trauma center experience from South Korea |
title_short | Implementation of a massive transfusion protocol: A single trauma center experience from South Korea |
title_sort | implementation of a massive transfusion protocol: a single trauma center experience from south korea |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277374/ https://www.ncbi.nlm.nih.gov/pubmed/36169455 http://dx.doi.org/10.14744/tjtes.2021.07824 |
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