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Immunohistochemical scoring of LAG-3 in conjunction with CD8 in the tumor microenvironment predicts response to immunotherapy in hepatocellular carcinoma

INTRODUCTION: Immune checkpoint blockade (ICB) is a systemic therapeutic option for advanced hepatocellular carcinoma (HCC). However, low patient response rates necessitate the development of robust predictive biomarkers that identify individuals who will benefit from ICB. A 4-gene inflammatory sign...

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Detalles Bibliográficos
Autores principales:	Cheung, Chun Chau Lawrence, Seah, Yong Hock Justin, Fang, Juntao, Orpilla, Nicole Hyacinth Calpatura, Lau, Mai Chan, Lim, Chun Jye, Lim, Xinru, Lee, Justina Nadia Li Wen, Lim, Jeffrey Chun Tatt, Lim, Sherlly, Cheng, Qing, Toh, Han Chong, Choo, Su Pin, Lee, Suat Ying, Lee, Joycelyn Jie Xin, Liu, Jin, Lim, Tony Kiat Hon, Tai, David, Yeong, Joe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277502/ https://www.ncbi.nlm.nih.gov/pubmed/37342338 http://dx.doi.org/10.3389/fimmu.2023.1150985

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