Cargando…
Immunohistochemical scoring of LAG-3 in conjunction with CD8 in the tumor microenvironment predicts response to immunotherapy in hepatocellular carcinoma
INTRODUCTION: Immune checkpoint blockade (ICB) is a systemic therapeutic option for advanced hepatocellular carcinoma (HCC). However, low patient response rates necessitate the development of robust predictive biomarkers that identify individuals who will benefit from ICB. A 4-gene inflammatory sign...
Autores principales: | Cheung, Chun Chau Lawrence, Seah, Yong Hock Justin, Fang, Juntao, Orpilla, Nicole Hyacinth Calpatura, Lau, Mai Chan, Lim, Chun Jye, Lim, Xinru, Lee, Justina Nadia Li Wen, Lim, Jeffrey Chun Tatt, Lim, Sherlly, Cheng, Qing, Toh, Han Chong, Choo, Su Pin, Lee, Suat Ying, Lee, Joycelyn Jie Xin, Liu, Jin, Lim, Tony Kiat Hon, Tai, David, Yeong, Joe |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277502/ https://www.ncbi.nlm.nih.gov/pubmed/37342338 http://dx.doi.org/10.3389/fimmu.2023.1150985 |
Ejemplares similares
-
Immunohistochemical scoring of CD38 in the tumor microenvironment predicts responsiveness to anti-PD-1/PD-L1 immunotherapy in hepatocellular carcinoma
por: Ng, Harry Ho Man, et al.
Publicado: (2020) -
The Roles of CD38 and CD157 in the Solid Tumor Microenvironment and Cancer Immunotherapy
por: Wo, Yu Jun, et al.
Publicado: (2019) -
Multimodal molecular landscape of response to Y90-resin microsphere radioembolization followed by nivolumab for advanced hepatocellular carcinoma
por: Kaya, Neslihan Arife, et al.
Publicado: (2023) -
Case report: Understanding the impact of persistent tissue-localization of SARS-CoV-2 on immune response activity via spatial transcriptomic analysis of two cancer patients with COVID-19 co-morbidity
por: Lau, Mai Chan, et al.
Publicado: (2022) -
Spatial transcriptomics reveal topological immune landscapes of Asian head and neck angiosarcoma
por: Loh, Jui Wan, et al.
Publicado: (2023)