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The spontaneous immortalization probability of mammalian cell culture strains, as their proliferative capacity, correlates with species body mass, not longevity
BACKGROUND: The Peto's paradox consists in the observation that individuals from long-lived and large animal species do not experience a higher cancer incidence, despite being exposed for longer time to the possibility of accumulating mutations and having more target cells exposed to the phenom...
Autores principales: | Perillo, Matteo, Punzo, Angela, Caliceti, Cristiana, Sell, Christian, Lorenzini, Antonello |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chang Gung University
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277518/ https://www.ncbi.nlm.nih.gov/pubmed/37149260 http://dx.doi.org/10.1016/j.bj.2023.100596 |
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