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The spontaneous immortalization probability of mammalian cell culture strains, as their proliferative capacity, correlates with species body mass, not longevity

BACKGROUND: The Peto's paradox consists in the observation that individuals from long-lived and large animal species do not experience a higher cancer incidence, despite being exposed for longer time to the possibility of accumulating mutations and having more target cells exposed to the phenom...

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Detalles Bibliográficos
Autores principales: Perillo, Matteo, Punzo, Angela, Caliceti, Cristiana, Sell, Christian, Lorenzini, Antonello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chang Gung University 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277518/
https://www.ncbi.nlm.nih.gov/pubmed/37149260
http://dx.doi.org/10.1016/j.bj.2023.100596

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