Free heme exacerbates colonic injury induced by anti-cancer therapy

Gastrointestinal inflammation and bleeding are commonly induced by cancer radiotherapy and chemotherapy but mechanisms are unclear. We demonstrated an increased number of infiltrating heme oxygenase-1 positive (HO-1+) macrophages (Mø, CD68+) and the levels of hemopexin (Hx) in human colonic biopsies...

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Detalles Bibliográficos
Autores principales: Seika, Philippa, Janikova, Monika, Asokan, Sahana, Janovicova, Lubica, Csizmadia, Eva, O’Connell, Mckenzie, Robson, Simon C., Glickman, Jonathan, Wegiel, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277564/
https://www.ncbi.nlm.nih.gov/pubmed/37342339
http://dx.doi.org/10.3389/fimmu.2023.1184105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277564/
https://www.ncbi.nlm.nih.gov/pubmed/37342339
http://dx.doi.org/10.3389/fimmu.2023.1184105

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