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Pathological tissue formation and degradation biomarkers correlate with patient reported pain outcomes: an explorative study
BACKGROUND: The lack of disease modifying drugs in Osteoarthritis (OA) may be attributed to the difficulty in robust response based on patient-reported outcomes (PROs) linked to drug mechanism of action. Joint tissue turnover biomarkers are associated with disease progression. A subset of patients h...
Autores principales: | Bay-Jensen, Anne C., Attur, Mukundan, Samuels, Jonathan, Thudium, Christian S., Abramson, Steven B., Karsdal, Morten A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277584/ https://www.ncbi.nlm.nih.gov/pubmed/37342785 http://dx.doi.org/10.1016/j.ocarto.2023.100379 |
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