Precise modification of the surface charge of antigen enhances vaccine immunogenicity

Aluminum (alum) adjuvant is the most extensively used protein subunit vaccine adjuvant, and its effectiveness and safety have been widely recognized. The surface charge of the antigen determines its electrostatic adsorption to alum adjuvant, which directly affects the immune efficacy of the protein...

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Detalles Bibliográficos
Autores principales: Zai, Xiaodong, Zhang, Zhiling, Zhou, Chuge, Zhao, Fangxin, Zhang, Yue, Wang, Xiaolin, Li, Ruihua, Li, Yaohui, Zhao, Xiaofan, Wang, Shuyi, Yang, Yilong, Yin, Ying, Zhang, Jun, Xu, Junjie, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277596/
https://www.ncbi.nlm.nih.gov/pubmed/37342672
http://dx.doi.org/10.1016/j.xinn.2023.100451

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