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Characterization of global research trends and prospects on platinum-resistant ovarian cancer: a bibliometric analysis
BACKGROUND: In the last decades, growing attention has been focused on identifying effective therapeutic strategies in the orphan clinical setting of women with platinum-resistant ovarian cancer (PROC), generating thousands of original articles. However, the literature involving bibliometric analysi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277726/ https://www.ncbi.nlm.nih.gov/pubmed/37342181 http://dx.doi.org/10.3389/fonc.2023.1151871 |
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author | Duan, Yuanqiong Zhang, Peixuan Zhang, Tianyue Zhou, Lu Yin, Rutie |
author_facet | Duan, Yuanqiong Zhang, Peixuan Zhang, Tianyue Zhou, Lu Yin, Rutie |
author_sort | Duan, Yuanqiong |
collection | PubMed |
description | BACKGROUND: In the last decades, growing attention has been focused on identifying effective therapeutic strategies in the orphan clinical setting of women with platinum-resistant ovarian cancer (PROC), generating thousands of original articles. However, the literature involving bibliometric analysis of PROC has not been published yet. OBJECTIVE: This study hopes to gain a better understanding of the hot spots and trends in PROC by conducting a bibliometric analysis, as well as identify potential new research directions. METHODS: We searched the Web of Science Core Collection (WOSCC) for PROC-related articles published between 1990 and 2022. CiteSpace 6.1.R2 and VOS viewer 1.6.18.0 were primarily utilized to evaluate the contribution and co-occurrence relationships of various countries and regions, institutes, and journals and to identify research hotspots and promising future trends in this research field. RESULTS: A total of 3,462 Web of Science publications were retrieved that were published in 671 academic journals by 1135 authors from 844 organizations in 75 countries and regions. The United States was the leading contributor in this field, and the University of Texas MD Anderson Cancer Center was the most productive institution. Gynecologic Oncology was the most productive journal, while the Journal of Clinical Oncology was the most cited and influential. Co-citation cluster labels revealed the characteristics of seven major clusters, including synthetic lethality, salvage treatment, human ovarian-carcinoma cell line, PARP inhibitor resistance, antitumor complexes, folate receptor, and targeting platinum-resistant disease. Keywords and references burst detection indicated that biomarkers, genetic and phenotypic changes, immunotherapy, and targeted therapy were the most recent and most significant aspects of PROC research. CONCLUSION: This study conducted a comprehensive review of PROC research using bibliometric and visual techniques. Understanding the immunological landscape of PROC and identifying the population that can benefit from immunotherapy, especially in combination with other therapeutic options (such as chemotherapy and targeted therapy), will continue to be the focal point of research. |
format | Online Article Text |
id | pubmed-10277726 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-102777262023-06-20 Characterization of global research trends and prospects on platinum-resistant ovarian cancer: a bibliometric analysis Duan, Yuanqiong Zhang, Peixuan Zhang, Tianyue Zhou, Lu Yin, Rutie Front Oncol Oncology BACKGROUND: In the last decades, growing attention has been focused on identifying effective therapeutic strategies in the orphan clinical setting of women with platinum-resistant ovarian cancer (PROC), generating thousands of original articles. However, the literature involving bibliometric analysis of PROC has not been published yet. OBJECTIVE: This study hopes to gain a better understanding of the hot spots and trends in PROC by conducting a bibliometric analysis, as well as identify potential new research directions. METHODS: We searched the Web of Science Core Collection (WOSCC) for PROC-related articles published between 1990 and 2022. CiteSpace 6.1.R2 and VOS viewer 1.6.18.0 were primarily utilized to evaluate the contribution and co-occurrence relationships of various countries and regions, institutes, and journals and to identify research hotspots and promising future trends in this research field. RESULTS: A total of 3,462 Web of Science publications were retrieved that were published in 671 academic journals by 1135 authors from 844 organizations in 75 countries and regions. The United States was the leading contributor in this field, and the University of Texas MD Anderson Cancer Center was the most productive institution. Gynecologic Oncology was the most productive journal, while the Journal of Clinical Oncology was the most cited and influential. Co-citation cluster labels revealed the characteristics of seven major clusters, including synthetic lethality, salvage treatment, human ovarian-carcinoma cell line, PARP inhibitor resistance, antitumor complexes, folate receptor, and targeting platinum-resistant disease. Keywords and references burst detection indicated that biomarkers, genetic and phenotypic changes, immunotherapy, and targeted therapy were the most recent and most significant aspects of PROC research. CONCLUSION: This study conducted a comprehensive review of PROC research using bibliometric and visual techniques. Understanding the immunological landscape of PROC and identifying the population that can benefit from immunotherapy, especially in combination with other therapeutic options (such as chemotherapy and targeted therapy), will continue to be the focal point of research. Frontiers Media S.A. 2023-06-05 /pmc/articles/PMC10277726/ /pubmed/37342181 http://dx.doi.org/10.3389/fonc.2023.1151871 Text en Copyright © 2023 Duan, Zhang, Zhang, Zhou and Yin https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Oncology Duan, Yuanqiong Zhang, Peixuan Zhang, Tianyue Zhou, Lu Yin, Rutie Characterization of global research trends and prospects on platinum-resistant ovarian cancer: a bibliometric analysis |
title | Characterization of global research trends and prospects on platinum-resistant ovarian cancer: a bibliometric analysis |
title_full | Characterization of global research trends and prospects on platinum-resistant ovarian cancer: a bibliometric analysis |
title_fullStr | Characterization of global research trends and prospects on platinum-resistant ovarian cancer: a bibliometric analysis |
title_full_unstemmed | Characterization of global research trends and prospects on platinum-resistant ovarian cancer: a bibliometric analysis |
title_short | Characterization of global research trends and prospects on platinum-resistant ovarian cancer: a bibliometric analysis |
title_sort | characterization of global research trends and prospects on platinum-resistant ovarian cancer: a bibliometric analysis |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277726/ https://www.ncbi.nlm.nih.gov/pubmed/37342181 http://dx.doi.org/10.3389/fonc.2023.1151871 |
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