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An Advax-CpG55.2™ adjuvanted recombinant spike protein vaccine protects cynomolgus macaques from a homologous SARS-CoV-2 virus challenge
Traditional protein-based vaccine approaches to COVID-19 were overshadowed by the new mRNA and adenoviral vector vaccine approaches which were first to receive marketing authorization. The current study tested for the first time in repurposed aged (median 15.4 years) cynomolgus macaques, a novel Adv...
Autores principales: | Honda-Okubo, Yoshikazu, Li, Lei, André, Greiciely, Leong, King Ho, Howerth, Elizabeth W., Bebin-Blackwell, Anne G., Ross, Ted M., Petrovsky, Nikolai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277844/ https://www.ncbi.nlm.nih.gov/pubmed/37355452 http://dx.doi.org/10.1016/j.vaccine.2023.06.063 |
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