Patient-derived melanoma organoid models facilitate the assessment of immunotherapies

BACKGROUND: Only a minority of melanoma patients experience durable responses to immunotherapies due to inter- and intra-tumoral heterogeneity in melanoma. As a result, there is a pressing need for suitable preclinical models to investigate resistance mechanisms and enhance treatment efficacy. METHO...

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Detalles Bibliográficos
Autores principales: Ou, Lingling, Liu, Shujing, Wang, Huaishan, Guo, Yeye, Guan, Lei, Shen, Longbin, Luo, Ruhui, Elder, David E., Huang, Alexander C., Karakousis, Giorgos, Miura, John, Mitchell, Tara, Schuchter, Lynn, Amaravadi, Ravi, Flowers, Ahron, Mou, Haiwei, Yi, Fan, Guo, Wei, Ko, Jina, Chen, Qing, Tian, Bin, Herlyn, Meenhard, Xu, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277922/
https://www.ncbi.nlm.nih.gov/pubmed/37229906
http://dx.doi.org/10.1016/j.ebiom.2023.104614

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