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DNAzymes: Expanding the Potential of Nucleic Acid Therapeutics

Nucleic acids drugs have been proven in the clinic as a powerful modality to treat inherited and acquired diseases. However, key challenges including drug stability, renal clearance, cellular uptake, and movement across biological barriers (foremost the blood–brain barrier) limit the translation and...

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Detalles Bibliográficos
Autores principales:	Larcher, Leon M., Pitout, Ianthe L., Keegan, Niall P., Veedu, Rakesh N., Fletcher, Sue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mary Ann Liebert, Inc., publishers 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278027/ https://www.ncbi.nlm.nih.gov/pubmed/37093127 http://dx.doi.org/10.1089/nat.2022.0066

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