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Genetically Encoded Aminocoumarin Lysine for Optical Control of Protein–Nucleotide Interactions in Zebrafish Embryos

[Image: see text] The strategic placement of unnatural amino acids into the active site of kinases and phosphatases has allowed for the generation of photocaged signaling proteins that offer spatiotemporal control over activation of these pathways through precise light exposure. However, deploying t...

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Detalles Bibliográficos
Autores principales: Brown, Wes, Wesalo, Joshua, Samanta, Subhas, Luo, Ji, Caldwell, Steven E., Tsang, Michael, Deiters, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278064/
https://www.ncbi.nlm.nih.gov/pubmed/37272594
http://dx.doi.org/10.1021/acschembio.3c00028