RNA aptamers with specific binding affinity to CD40 (CD40Apt) represents a promising antagonist of the CD40-CD40L signaling for thyroid-associated ophthalmopathy (TAO) treatment in mouse

Thyroid-associated ophthalmopathy (TAO) is the most common autoimmune inflammatory diseases of the orbit. The CD40-CD40L pathway has been regarded as a potential molecular mechanism contributing to the development and progression of TAO, and RNA aptamers with specific binding affinity to CD40 (CD40A...

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Detalles Bibliográficos
Autores principales: Chen, Yizhi, Tang, Renhong, Xiong, Wei, Zhang, Feng, Wang, Nuo, Xie, Bingyu, Cao, Jiamin, Chen, Zhuokun, Ma, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278284/
https://www.ncbi.nlm.nih.gov/pubmed/37331977
http://dx.doi.org/10.1186/s12967-023-04217-0

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