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Ramucirumab plus irinotecan / leucovorin / 5-FU versus ramucirumab plus paclitaxel in patients with advanced or metastatic adenocarcinoma of the stomach or gastroesophageal junction, who failed one prior line of palliative chemotherapy: the phase II/III RAMIRIS study (AIO-STO-0415)
BACKGROUND: Paclitaxel in combination with ramucirumab is the standard of care second-line therapy in gastro-esophageal adenocarcinoma (GEA). As the number of taxane pretreated patients in the perioperative or first-line setting is increasing, it is unknown whether these patients benefit from re-app...
Autores principales: | Lorenzen, Sylvie, Schwarz, Alix, Pauligk, Claudia, Goekkurt, Eray, Stocker, Gertraud, Knorrenschild, Jorge Riera, Illerhaus, Gerald, Dechow, Tobias, Moehler, Markus, Moulin, Jean-Charles, Pink, Daniel, Stahl, Michael, Schaaf, Marina, Goetze, Thorsten Oliver, Al-Batran, Salah-Eddin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278289/ https://www.ncbi.nlm.nih.gov/pubmed/37337155 http://dx.doi.org/10.1186/s12885-023-11004-z |
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