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Local GHR roles in regulation of mitochondrial function through mitochondrial biogenesis during myoblast differentiation

BACKGROUND: Myoblast differentiation requires metabolic reprogramming driven by increased mitochondrial biogenesis and oxidative phosphorylation. The canonical GH-GHR-IGFs axis in liver exhibits a great complexity in response to somatic growth. However, the underlying mechanism of whether local GHR...

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Detalles Bibliográficos
Autores principales: Hu, Bowen, Zhao, Changbin, Pan, Xiangchun, Wei, Haohui, Mo, Guodong, Xian, Mingjian, Luo, Wen, Nie, Qinghua, Li, Hongmei, Zhang, Xiquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278349/
https://www.ncbi.nlm.nih.gov/pubmed/37337300
http://dx.doi.org/10.1186/s12964-023-01166-5