Cargando…

Targeting GITR in cancer immunotherapy – there is no perfect knowledge

Glucocorticoid-induced TNFR-related protein (GITR) belongs to the TNFR superfamily (TNFRSF) and stimulates both the acquired and innate immunity. GITR is broadly expressed on immune cells, particularly regulatory T cells (Tregs) and natural killer (NK) cells. Given its potential to promote T effecto...

Descripción completa

Detalles Bibliográficos
Autores principales: Davar, Diwakar, Zappasodi, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278658/
https://www.ncbi.nlm.nih.gov/pubmed/37335294
http://dx.doi.org/10.18632/oncotarget.28461