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IGFBP-3 promotes cachexia-associated lipid loss by suppressing insulin-like growth factor/insulin signaling

BACKGROUND: Progressive lipid loss of adipose tissue is a major feature of cancer-associated cachexia. In addition to systemic immune/inflammatory effects in response to tumor progression, tumor-secreted cachectic ligands also play essential roles in tumor-induced lipid loss. However, the mechanisms...

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Detalles Bibliográficos
Autores principales:	Wang, Xiaohui, Li, Jia, Zhang, Wei, Wang, Feng, Wu, Yunzi, Guo, Yulin, Wang, Dong, Yu, Xinfeng, Li, Ang, Li, Fei, Xie, Yibin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2003
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278738/ https://www.ncbi.nlm.nih.gov/pubmed/37014770 http://dx.doi.org/10.1097/CM9.0000000000002628

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