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Tissue Inhibitor Metalloproteinase-2 and Insulin-Like Growth Factor Binding Protein-7 Kinetics Following Exposure to High-Dose Methotrexate

Urinary TIMP2×IGFBP7 (uTIMP2×IGFBP7) concentrations experienced a rapid and sustained decline after high-dose methotrexate (MTX) exposure. uTIMP2×IGFBP7 kinetics and concentrations after high-dose MTX exposure demonstrated no utility in predicting AKI.

Detalles Bibliográficos
Autores principales: Barreto, Jason N., Barreto, Erin F., Mara, Kristin C., Rule, Andrew D., Lieske, John C., Giesen, Callen D., Thompson, Carrie A., Leung, Nelson, Witzig, Thomas E., Kashani, Kianoush B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Nephrology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278852/
https://www.ncbi.nlm.nih.gov/pubmed/36888987
http://dx.doi.org/10.34067/KID.0000000000000099
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author Barreto, Jason N.
Barreto, Erin F.
Mara, Kristin C.
Rule, Andrew D.
Lieske, John C.
Giesen, Callen D.
Thompson, Carrie A.
Leung, Nelson
Witzig, Thomas E.
Kashani, Kianoush B.
author_facet Barreto, Jason N.
Barreto, Erin F.
Mara, Kristin C.
Rule, Andrew D.
Lieske, John C.
Giesen, Callen D.
Thompson, Carrie A.
Leung, Nelson
Witzig, Thomas E.
Kashani, Kianoush B.
author_sort Barreto, Jason N.
collection PubMed
description Urinary TIMP2×IGFBP7 (uTIMP2×IGFBP7) concentrations experienced a rapid and sustained decline after high-dose methotrexate (MTX) exposure. uTIMP2×IGFBP7 kinetics and concentrations after high-dose MTX exposure demonstrated no utility in predicting AKI.
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spelling pubmed-102788522023-08-03 Tissue Inhibitor Metalloproteinase-2 and Insulin-Like Growth Factor Binding Protein-7 Kinetics Following Exposure to High-Dose Methotrexate Barreto, Jason N. Barreto, Erin F. Mara, Kristin C. Rule, Andrew D. Lieske, John C. Giesen, Callen D. Thompson, Carrie A. Leung, Nelson Witzig, Thomas E. Kashani, Kianoush B. Kidney360 Brief Communication Urinary TIMP2×IGFBP7 (uTIMP2×IGFBP7) concentrations experienced a rapid and sustained decline after high-dose methotrexate (MTX) exposure. uTIMP2×IGFBP7 kinetics and concentrations after high-dose MTX exposure demonstrated no utility in predicting AKI. American Society of Nephrology 2023-03-08 /pmc/articles/PMC10278852/ /pubmed/36888987 http://dx.doi.org/10.34067/KID.0000000000000099 Text en Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Society of Nephrology https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CC-BY) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Brief Communication
Barreto, Jason N.
Barreto, Erin F.
Mara, Kristin C.
Rule, Andrew D.
Lieske, John C.
Giesen, Callen D.
Thompson, Carrie A.
Leung, Nelson
Witzig, Thomas E.
Kashani, Kianoush B.
Tissue Inhibitor Metalloproteinase-2 and Insulin-Like Growth Factor Binding Protein-7 Kinetics Following Exposure to High-Dose Methotrexate
title Tissue Inhibitor Metalloproteinase-2 and Insulin-Like Growth Factor Binding Protein-7 Kinetics Following Exposure to High-Dose Methotrexate
title_full Tissue Inhibitor Metalloproteinase-2 and Insulin-Like Growth Factor Binding Protein-7 Kinetics Following Exposure to High-Dose Methotrexate
title_fullStr Tissue Inhibitor Metalloproteinase-2 and Insulin-Like Growth Factor Binding Protein-7 Kinetics Following Exposure to High-Dose Methotrexate
title_full_unstemmed Tissue Inhibitor Metalloproteinase-2 and Insulin-Like Growth Factor Binding Protein-7 Kinetics Following Exposure to High-Dose Methotrexate
title_short Tissue Inhibitor Metalloproteinase-2 and Insulin-Like Growth Factor Binding Protein-7 Kinetics Following Exposure to High-Dose Methotrexate
title_sort tissue inhibitor metalloproteinase-2 and insulin-like growth factor binding protein-7 kinetics following exposure to high-dose methotrexate
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278852/
https://www.ncbi.nlm.nih.gov/pubmed/36888987
http://dx.doi.org/10.34067/KID.0000000000000099
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