Cargando…
Tissue Inhibitor Metalloproteinase-2 and Insulin-Like Growth Factor Binding Protein-7 Kinetics Following Exposure to High-Dose Methotrexate
Urinary TIMP2×IGFBP7 (uTIMP2×IGFBP7) concentrations experienced a rapid and sustained decline after high-dose methotrexate (MTX) exposure. uTIMP2×IGFBP7 kinetics and concentrations after high-dose MTX exposure demonstrated no utility in predicting AKI.
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Nephrology
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278852/ https://www.ncbi.nlm.nih.gov/pubmed/36888987 http://dx.doi.org/10.34067/KID.0000000000000099 |
_version_ | 1785060553371156480 |
---|---|
author | Barreto, Jason N. Barreto, Erin F. Mara, Kristin C. Rule, Andrew D. Lieske, John C. Giesen, Callen D. Thompson, Carrie A. Leung, Nelson Witzig, Thomas E. Kashani, Kianoush B. |
author_facet | Barreto, Jason N. Barreto, Erin F. Mara, Kristin C. Rule, Andrew D. Lieske, John C. Giesen, Callen D. Thompson, Carrie A. Leung, Nelson Witzig, Thomas E. Kashani, Kianoush B. |
author_sort | Barreto, Jason N. |
collection | PubMed |
description | Urinary TIMP2×IGFBP7 (uTIMP2×IGFBP7) concentrations experienced a rapid and sustained decline after high-dose methotrexate (MTX) exposure. uTIMP2×IGFBP7 kinetics and concentrations after high-dose MTX exposure demonstrated no utility in predicting AKI. |
format | Online Article Text |
id | pubmed-10278852 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | American Society of Nephrology |
record_format | MEDLINE/PubMed |
spelling | pubmed-102788522023-08-03 Tissue Inhibitor Metalloproteinase-2 and Insulin-Like Growth Factor Binding Protein-7 Kinetics Following Exposure to High-Dose Methotrexate Barreto, Jason N. Barreto, Erin F. Mara, Kristin C. Rule, Andrew D. Lieske, John C. Giesen, Callen D. Thompson, Carrie A. Leung, Nelson Witzig, Thomas E. Kashani, Kianoush B. Kidney360 Brief Communication Urinary TIMP2×IGFBP7 (uTIMP2×IGFBP7) concentrations experienced a rapid and sustained decline after high-dose methotrexate (MTX) exposure. uTIMP2×IGFBP7 kinetics and concentrations after high-dose MTX exposure demonstrated no utility in predicting AKI. American Society of Nephrology 2023-03-08 /pmc/articles/PMC10278852/ /pubmed/36888987 http://dx.doi.org/10.34067/KID.0000000000000099 Text en Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Society of Nephrology https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CC-BY) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. |
spellingShingle | Brief Communication Barreto, Jason N. Barreto, Erin F. Mara, Kristin C. Rule, Andrew D. Lieske, John C. Giesen, Callen D. Thompson, Carrie A. Leung, Nelson Witzig, Thomas E. Kashani, Kianoush B. Tissue Inhibitor Metalloproteinase-2 and Insulin-Like Growth Factor Binding Protein-7 Kinetics Following Exposure to High-Dose Methotrexate |
title | Tissue Inhibitor Metalloproteinase-2 and Insulin-Like Growth Factor Binding Protein-7 Kinetics Following Exposure to High-Dose Methotrexate |
title_full | Tissue Inhibitor Metalloproteinase-2 and Insulin-Like Growth Factor Binding Protein-7 Kinetics Following Exposure to High-Dose Methotrexate |
title_fullStr | Tissue Inhibitor Metalloproteinase-2 and Insulin-Like Growth Factor Binding Protein-7 Kinetics Following Exposure to High-Dose Methotrexate |
title_full_unstemmed | Tissue Inhibitor Metalloproteinase-2 and Insulin-Like Growth Factor Binding Protein-7 Kinetics Following Exposure to High-Dose Methotrexate |
title_short | Tissue Inhibitor Metalloproteinase-2 and Insulin-Like Growth Factor Binding Protein-7 Kinetics Following Exposure to High-Dose Methotrexate |
title_sort | tissue inhibitor metalloproteinase-2 and insulin-like growth factor binding protein-7 kinetics following exposure to high-dose methotrexate |
topic | Brief Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278852/ https://www.ncbi.nlm.nih.gov/pubmed/36888987 http://dx.doi.org/10.34067/KID.0000000000000099 |
work_keys_str_mv | AT barretojasonn tissueinhibitormetalloproteinase2andinsulinlikegrowthfactorbindingprotein7kineticsfollowingexposuretohighdosemethotrexate AT barretoerinf tissueinhibitormetalloproteinase2andinsulinlikegrowthfactorbindingprotein7kineticsfollowingexposuretohighdosemethotrexate AT marakristinc tissueinhibitormetalloproteinase2andinsulinlikegrowthfactorbindingprotein7kineticsfollowingexposuretohighdosemethotrexate AT ruleandrewd tissueinhibitormetalloproteinase2andinsulinlikegrowthfactorbindingprotein7kineticsfollowingexposuretohighdosemethotrexate AT lieskejohnc tissueinhibitormetalloproteinase2andinsulinlikegrowthfactorbindingprotein7kineticsfollowingexposuretohighdosemethotrexate AT giesencallend tissueinhibitormetalloproteinase2andinsulinlikegrowthfactorbindingprotein7kineticsfollowingexposuretohighdosemethotrexate AT thompsoncarriea tissueinhibitormetalloproteinase2andinsulinlikegrowthfactorbindingprotein7kineticsfollowingexposuretohighdosemethotrexate AT leungnelson tissueinhibitormetalloproteinase2andinsulinlikegrowthfactorbindingprotein7kineticsfollowingexposuretohighdosemethotrexate AT witzigthomase tissueinhibitormetalloproteinase2andinsulinlikegrowthfactorbindingprotein7kineticsfollowingexposuretohighdosemethotrexate AT kashanikianoushb tissueinhibitormetalloproteinase2andinsulinlikegrowthfactorbindingprotein7kineticsfollowingexposuretohighdosemethotrexate |