Altered hACE2 binding affinity and S1/S2 cleavage efficiency of SARS-CoV-2 spike protein mutants affect viral cell entry

SARS-CoV-2 variants are constantly emerging, hampering public health measures in controlling the number of infections. While it is well established that mutations in spike proteins observed for the different variants directly affect virus entry into host cells, there remains a need for further expan...

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Detalles Bibliográficos
Autores principales: Wang, Ke, Pan, Yu, Wang, Dianbing, Yuan, Ye, Li, Min, Chen, Yuanyuan, Bi, Lijun, Zhang, Xian-En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wuhan Institute of Virology, Chinese Academy of Sciences 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278895/
https://www.ncbi.nlm.nih.gov/pubmed/37343929
http://dx.doi.org/10.1016/j.virs.2023.06.005

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