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Endogenous Amyloid-formed Ca(2+)-permeable Channels in Aged 3xTg AD Mice

Alzheimer’s disease (AD), the leading cause of dementia, is characterized by the accumulation of beta-amyloid peptides (Aβ). However, whether Aβ itself is a key toxic agent in AD pathogenesis and the precise mechanism of Aβ-elicited neurotoxicity are still debated. Emerging evidence demonstrates tha...

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Detalles Bibliográficos
Autores principales: Li, Shuangtao, Ji, Xiaoyu, Gao, Ming, Huang, Bing, Peng, Shuang, Wu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278988/
https://www.ncbi.nlm.nih.gov/pubmed/37342418
http://dx.doi.org/10.1093/function/zqad025