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Protection of Catalytic Cofactors by Polypeptides as a Driver for the Emergence of Primordial Enzymes
Enzymes catalyze the chemical reactions of life. For nearly half of known enzymes, catalysis requires the binding of small molecules known as cofactors. Polypeptide-cofactor complexes likely formed at a primordial stage and became starting points for the evolution of many efficient enzymes. Yet, evo...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279418/ https://www.ncbi.nlm.nih.gov/pubmed/37235753 http://dx.doi.org/10.1093/molbev/msad126 |