Hi-plex deep amplicon sequencing for identification, high-resolution genotyping and multidrug resistance prediction of Mycobacterium leprae directly from patient biopsies by using Deeplex Myc-Lep

BACKGROUND: Expansion of antimicrobial resistance monitoring and epidemiological surveillance are key components of the WHO strategy towards zero leprosy. The inability to grow Mycobacterium leprae in vitro precludes routine phenotypic drug susceptibility testing, and only limited molecular tests ar...

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Detalles Bibliográficos
Autores principales: Jouet, Agathe, Braet, Sofie Marijke, Gaudin, Cyril, Bisch, Gaëlle, Vasconcellos, Sidra, Epaminondas Nicacio de Oliveira do Livramento, Rebecca Emmanuela, Prado Palacios, Yrneh Yadamis, Fontes, Amanda Brum, Lucena, Norma, Rosa, Patricia, Moraes, Milton, La, Kevin, Badalato, Nelly, Lenoir, Esteban, Ferré, Alice, Clément, Marie, Hasker, Epco, Grillone, Silahi Halifa, Abdou, Wirdane, Said, Aouladi, Assoumani, Younoussa, Attoumani, Nissad, Laurent, Yannick, Cambau, Emmanuelle, de Jong, Bouke Catherine, Suffys, Philip Noël, Supply, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279541/
https://www.ncbi.nlm.nih.gov/pubmed/37327675
http://dx.doi.org/10.1016/j.ebiom.2023.104649

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