HFrEF subphenotypes based on 4210 repeatedly measured circulating proteins are driven by different biological mechanisms

BACKGROUND: HFrEF is a heterogenous condition with high mortality. We used serial assessments of 4210 circulating proteins to identify distinct novel protein-based HFrEF subphenotypes and to investigate underlying dynamic biological mechanisms. Herewith we aimed to gain pathophysiological insights a...

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Detalles Bibliográficos
Autores principales: Petersen, Teun B., de Bakker, Marie, Asselbergs, Folkert W., Harakalova, Magdalena, Akkerhuis, K. Martijn, Brugts, Jasper J., van Ramshorst, Jan, Lumbers, R. Thomas, Ostroff, Rachel M., Katsikis, Peter D., van der Spek, Peter J., Umans, Victor A., Boersma, Eric, Rizopoulos, Dimitris, Kardys, Isabella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279550/
https://www.ncbi.nlm.nih.gov/pubmed/37327673
http://dx.doi.org/10.1016/j.ebiom.2023.104655

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