Immune compartments at the brain’s borders in health and neurovascular diseases

Recent evidence implicates cranial border immune compartments in the meninges, choroid plexus, circumventricular organs, and skull bone marrow in several neuroinflammatory and neoplastic diseases. Their pathogenic importance has also been described for cardiovascular diseases such as hypertension an...

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Autores principales: Goertz, Jennifer E., Garcia-Bonilla, Lidia, Iadecola, Costantino, Anrather, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279585/
https://www.ncbi.nlm.nih.gov/pubmed/37138042
http://dx.doi.org/10.1007/s00281-023-00992-6
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author Goertz, Jennifer E.
Garcia-Bonilla, Lidia
Iadecola, Costantino
Anrather, Josef
author_facet Goertz, Jennifer E.
Garcia-Bonilla, Lidia
Iadecola, Costantino
Anrather, Josef
author_sort Goertz, Jennifer E.
collection PubMed
description Recent evidence implicates cranial border immune compartments in the meninges, choroid plexus, circumventricular organs, and skull bone marrow in several neuroinflammatory and neoplastic diseases. Their pathogenic importance has also been described for cardiovascular diseases such as hypertension and stroke. In this review, we will examine the cellular composition of these cranial border immune niches, the potential pathways through which they might interact, and the evidence linking them to cardiovascular disease.
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spelling pubmed-102795852023-06-21 Immune compartments at the brain’s borders in health and neurovascular diseases Goertz, Jennifer E. Garcia-Bonilla, Lidia Iadecola, Costantino Anrather, Josef Semin Immunopathol Review Recent evidence implicates cranial border immune compartments in the meninges, choroid plexus, circumventricular organs, and skull bone marrow in several neuroinflammatory and neoplastic diseases. Their pathogenic importance has also been described for cardiovascular diseases such as hypertension and stroke. In this review, we will examine the cellular composition of these cranial border immune niches, the potential pathways through which they might interact, and the evidence linking them to cardiovascular disease. Springer Berlin Heidelberg 2023-05-03 2023 /pmc/articles/PMC10279585/ /pubmed/37138042 http://dx.doi.org/10.1007/s00281-023-00992-6 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review
Goertz, Jennifer E.
Garcia-Bonilla, Lidia
Iadecola, Costantino
Anrather, Josef
Immune compartments at the brain’s borders in health and neurovascular diseases
title Immune compartments at the brain’s borders in health and neurovascular diseases
title_full Immune compartments at the brain’s borders in health and neurovascular diseases
title_fullStr Immune compartments at the brain’s borders in health and neurovascular diseases
title_full_unstemmed Immune compartments at the brain’s borders in health and neurovascular diseases
title_short Immune compartments at the brain’s borders in health and neurovascular diseases
title_sort immune compartments at the brain’s borders in health and neurovascular diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279585/
https://www.ncbi.nlm.nih.gov/pubmed/37138042
http://dx.doi.org/10.1007/s00281-023-00992-6
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