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In-vivo corneal confocal microscopy: Imaging analysis, biological insights and future directions
In-vivo corneal confocal microscopy is a powerful imaging technique which provides clinicians and researcher with the capabilities to observe microstructures at the ocular surfaces in significant detail. In this Mini Review, the optics and image analysis methods with the use of corneal confocal micr...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279669/ https://www.ncbi.nlm.nih.gov/pubmed/37336941 http://dx.doi.org/10.1038/s42003-023-05005-8 |
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author | Chiang, Jeremy Chung Bo Roy, Maitreyee Kim, Juno Markoulli, Maria Krishnan, Arun V. |
author_facet | Chiang, Jeremy Chung Bo Roy, Maitreyee Kim, Juno Markoulli, Maria Krishnan, Arun V. |
author_sort | Chiang, Jeremy Chung Bo |
collection | PubMed |
description | In-vivo corneal confocal microscopy is a powerful imaging technique which provides clinicians and researcher with the capabilities to observe microstructures at the ocular surfaces in significant detail. In this Mini Review, the optics and image analysis methods with the use of corneal confocal microscopy are discussed. While novel insights of neuroanatomy and biology of the eyes, particularly the ocular surface, have been provided by corneal confocal microscopy, some debatable elements observed using this technique remain and these are explored in this Mini Review. Potential improvements in imaging methodology and instrumentation are also suggested. |
format | Online Article Text |
id | pubmed-10279669 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-102796692023-06-21 In-vivo corneal confocal microscopy: Imaging analysis, biological insights and future directions Chiang, Jeremy Chung Bo Roy, Maitreyee Kim, Juno Markoulli, Maria Krishnan, Arun V. Commun Biol Mini Review In-vivo corneal confocal microscopy is a powerful imaging technique which provides clinicians and researcher with the capabilities to observe microstructures at the ocular surfaces in significant detail. In this Mini Review, the optics and image analysis methods with the use of corneal confocal microscopy are discussed. While novel insights of neuroanatomy and biology of the eyes, particularly the ocular surface, have been provided by corneal confocal microscopy, some debatable elements observed using this technique remain and these are explored in this Mini Review. Potential improvements in imaging methodology and instrumentation are also suggested. Nature Publishing Group UK 2023-06-19 /pmc/articles/PMC10279669/ /pubmed/37336941 http://dx.doi.org/10.1038/s42003-023-05005-8 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Mini Review Chiang, Jeremy Chung Bo Roy, Maitreyee Kim, Juno Markoulli, Maria Krishnan, Arun V. In-vivo corneal confocal microscopy: Imaging analysis, biological insights and future directions |
title | In-vivo corneal confocal microscopy: Imaging analysis, biological insights and future directions |
title_full | In-vivo corneal confocal microscopy: Imaging analysis, biological insights and future directions |
title_fullStr | In-vivo corneal confocal microscopy: Imaging analysis, biological insights and future directions |
title_full_unstemmed | In-vivo corneal confocal microscopy: Imaging analysis, biological insights and future directions |
title_short | In-vivo corneal confocal microscopy: Imaging analysis, biological insights and future directions |
title_sort | in-vivo corneal confocal microscopy: imaging analysis, biological insights and future directions |
topic | Mini Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279669/ https://www.ncbi.nlm.nih.gov/pubmed/37336941 http://dx.doi.org/10.1038/s42003-023-05005-8 |
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