HIF-1α dependent RhoA as a novel therapeutic target to regulate rheumatoid arthritis fibroblast-like synoviocytes migration in vitro and in vivo

OBJECTIVE: The purpose of this work is to investigate how the Rho family of GTPases A (RhoA) mediates the pathogenesis of rheumatoid arthritis fibroblast-like synoviocytes (RA-FLS). METHODS: The expression of RhoA in the synovial tissues of RA and Healthy people (Control) was detected using immunohi...

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Detalles Bibliográficos
Autores principales: Chen, Jianhai, Chen, Jingqin, Tan, Jianwei, Li, Jian, Cheng, Wenxiang, Ke, Liqing, Wang, Qijing, Wang, Anqiao, Lin, Sien, Li, Gang, Zhang, Peng, Wang, Benguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279694/
https://www.ncbi.nlm.nih.gov/pubmed/37346290
http://dx.doi.org/10.1016/j.jot.2023.05.004

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