ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustion

The ATR kinase, which coordinates cellular responses to DNA replication stress, is also essential for the proliferation of normal unstressed cells. Although its role in the replication stress response is well defined, the mechanisms by which ATR supports normal cell proliferation remain elusive. Her...

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Detalles Bibliográficos
Autores principales: Menolfi, Demis, Lee, Brian J., Zhang, Hanwen, Jiang, Wenxia, Bowen, Nicole E., Wang, Yunyue, Zhao, Junfei, Holmes, Antony, Gershik, Steven, Rabadan, Raul, Kim, Baek, Zha, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279696/
https://www.ncbi.nlm.nih.gov/pubmed/37336885
http://dx.doi.org/10.1038/s41467-023-39332-5

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