Integrative scATAC-seq and scRNA-seq analyses map thymic iNKT cell development and identify Cbfβ for its commitment

Unlike conventional αβT cells, invariant natural killer T (iNKT) cells complete their terminal differentiation to functional iNKT1/2/17 cells in the thymus. However, underlying molecular programs that guide iNKT subset differentiation remain unclear. Here, we profiled the transcriptomes of over 17,0...

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Detalles Bibliográficos
Autores principales: Wang, Jie, Adrianto, Indra, Subedi, Kalpana, Liu, Tingting, Wu, Xiaojun, Yi, Qijun, Loveless, Ian, Yin, Congcong, Datta, Indrani, Sant’Angelo, Derek B., Kronenberg, Mitchell, Zhou, Li, Mi, Qing-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279728/
https://www.ncbi.nlm.nih.gov/pubmed/37336875
http://dx.doi.org/10.1038/s41421-023-00547-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279728/
https://www.ncbi.nlm.nih.gov/pubmed/37336875
http://dx.doi.org/10.1038/s41421-023-00547-x

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