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Integrative scATAC-seq and scRNA-seq analyses map thymic iNKT cell development and identify Cbfβ for its commitment
Unlike conventional αβT cells, invariant natural killer T (iNKT) cells complete their terminal differentiation to functional iNKT1/2/17 cells in the thymus. However, underlying molecular programs that guide iNKT subset differentiation remain unclear. Here, we profiled the transcriptomes of over 17,0...
Autores principales: | Wang, Jie, Adrianto, Indra, Subedi, Kalpana, Liu, Tingting, Wu, Xiaojun, Yi, Qijun, Loveless, Ian, Yin, Congcong, Datta, Indrani, Sant’Angelo, Derek B., Kronenberg, Mitchell, Zhou, Li, Mi, Qing-Sheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279728/ https://www.ncbi.nlm.nih.gov/pubmed/37336875 http://dx.doi.org/10.1038/s41421-023-00547-x |
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