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Recent medicinal approaches of novel pyrimidine analogs: A review
Pyrimidine derivatives attract researchers due to their versatile scaffold & their medicinal significance. Pyrimidine associated analogs are majorly contributed to the field of medicinal chemistry. In this review article, the recent new structural design and development of active agent studies a...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279829/ https://www.ncbi.nlm.nih.gov/pubmed/37346348 http://dx.doi.org/10.1016/j.heliyon.2023.e16773 |
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author | Patil, Sharanabasappa B. |
author_facet | Patil, Sharanabasappa B. |
author_sort | Patil, Sharanabasappa B. |
collection | PubMed |
description | Pyrimidine derivatives attract researchers due to their versatile scaffold & their medicinal significance. Pyrimidine associated analogs are majorly contributed to the field of medicinal chemistry. In this review article, the recent new structural design and development of active agent studies and biological approaches are highlighted. In addition, the biological potency and the structure-activity relationship of pyrimidines such as antimicrobial, anticancer, anti-inflammatory, analgesic, anti-diabetic, anti-HIV, anthelmintic, CNS depressants, and cardiac agents are discussed. Finally, this review article may attract the researchers for new structural design and development of novel active pyrimidine scaffolds with more active and less harmful. |
format | Online Article Text |
id | pubmed-10279829 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-102798292023-06-21 Recent medicinal approaches of novel pyrimidine analogs: A review Patil, Sharanabasappa B. Heliyon Review Article Pyrimidine derivatives attract researchers due to their versatile scaffold & their medicinal significance. Pyrimidine associated analogs are majorly contributed to the field of medicinal chemistry. In this review article, the recent new structural design and development of active agent studies and biological approaches are highlighted. In addition, the biological potency and the structure-activity relationship of pyrimidines such as antimicrobial, anticancer, anti-inflammatory, analgesic, anti-diabetic, anti-HIV, anthelmintic, CNS depressants, and cardiac agents are discussed. Finally, this review article may attract the researchers for new structural design and development of novel active pyrimidine scaffolds with more active and less harmful. Elsevier 2023-06-02 /pmc/articles/PMC10279829/ /pubmed/37346348 http://dx.doi.org/10.1016/j.heliyon.2023.e16773 Text en © 2023 The Author. Published by Elsevier Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Review Article Patil, Sharanabasappa B. Recent medicinal approaches of novel pyrimidine analogs: A review |
title | Recent medicinal approaches of novel pyrimidine analogs: A review |
title_full | Recent medicinal approaches of novel pyrimidine analogs: A review |
title_fullStr | Recent medicinal approaches of novel pyrimidine analogs: A review |
title_full_unstemmed | Recent medicinal approaches of novel pyrimidine analogs: A review |
title_short | Recent medicinal approaches of novel pyrimidine analogs: A review |
title_sort | recent medicinal approaches of novel pyrimidine analogs: a review |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279829/ https://www.ncbi.nlm.nih.gov/pubmed/37346348 http://dx.doi.org/10.1016/j.heliyon.2023.e16773 |
work_keys_str_mv | AT patilsharanabasappab recentmedicinalapproachesofnovelpyrimidineanalogsareview |