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Recent medicinal approaches of novel pyrimidine analogs: A review

Pyrimidine derivatives attract researchers due to their versatile scaffold & their medicinal significance. Pyrimidine associated analogs are majorly contributed to the field of medicinal chemistry. In this review article, the recent new structural design and development of active agent studies a...

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Autor principal: Patil, Sharanabasappa B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279829/
https://www.ncbi.nlm.nih.gov/pubmed/37346348
http://dx.doi.org/10.1016/j.heliyon.2023.e16773
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author Patil, Sharanabasappa B.
author_facet Patil, Sharanabasappa B.
author_sort Patil, Sharanabasappa B.
collection PubMed
description Pyrimidine derivatives attract researchers due to their versatile scaffold & their medicinal significance. Pyrimidine associated analogs are majorly contributed to the field of medicinal chemistry. In this review article, the recent new structural design and development of active agent studies and biological approaches are highlighted. In addition, the biological potency and the structure-activity relationship of pyrimidines such as antimicrobial, anticancer, anti-inflammatory, analgesic, anti-diabetic, anti-HIV, anthelmintic, CNS depressants, and cardiac agents are discussed. Finally, this review article may attract the researchers for new structural design and development of novel active pyrimidine scaffolds with more active and less harmful.
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spelling pubmed-102798292023-06-21 Recent medicinal approaches of novel pyrimidine analogs: A review Patil, Sharanabasappa B. Heliyon Review Article Pyrimidine derivatives attract researchers due to their versatile scaffold & their medicinal significance. Pyrimidine associated analogs are majorly contributed to the field of medicinal chemistry. In this review article, the recent new structural design and development of active agent studies and biological approaches are highlighted. In addition, the biological potency and the structure-activity relationship of pyrimidines such as antimicrobial, anticancer, anti-inflammatory, analgesic, anti-diabetic, anti-HIV, anthelmintic, CNS depressants, and cardiac agents are discussed. Finally, this review article may attract the researchers for new structural design and development of novel active pyrimidine scaffolds with more active and less harmful. Elsevier 2023-06-02 /pmc/articles/PMC10279829/ /pubmed/37346348 http://dx.doi.org/10.1016/j.heliyon.2023.e16773 Text en © 2023 The Author. Published by Elsevier Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Patil, Sharanabasappa B.
Recent medicinal approaches of novel pyrimidine analogs: A review
title Recent medicinal approaches of novel pyrimidine analogs: A review
title_full Recent medicinal approaches of novel pyrimidine analogs: A review
title_fullStr Recent medicinal approaches of novel pyrimidine analogs: A review
title_full_unstemmed Recent medicinal approaches of novel pyrimidine analogs: A review
title_short Recent medicinal approaches of novel pyrimidine analogs: A review
title_sort recent medicinal approaches of novel pyrimidine analogs: a review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279829/
https://www.ncbi.nlm.nih.gov/pubmed/37346348
http://dx.doi.org/10.1016/j.heliyon.2023.e16773
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