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Benzylisoquinoline alkaloids inhibit lung fibroblast activation mainly via inhibiting TGF-β1/Smads and ERK1/2 pathway proteins

BACKGROUNDS: Liensinine (Lien), Neferine (Nef), Isoliensinine (Iso) and Tetrandrine (Tet), benzylisoquinoline alkaloids (BIAs), have been shown inhibitory effects on pulmonary fibrosis (PF) through anti-inflammatory, anti-oxidative activities, inhibition of cytokines and NF-κB. Effects of other simi...

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Detalles Bibliográficos
Autores principales: Ren, Hui-Li, Zhang, Jia-Hua, Xiao, Jun-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279837/
https://www.ncbi.nlm.nih.gov/pubmed/37346334
http://dx.doi.org/10.1016/j.heliyon.2023.e16849