Dysfunction of von-Hippel Lindau factor causes reduced degradation of HIF leading to renal cancer. Hypoxia-inducible factor-prolyl hydroxylase enzyme inhibitors also lessen HIF destruction and could therefore increase renal cancer

Detalles Bibliográficos
Autor principal: Waldum, Helge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279847/
https://www.ncbi.nlm.nih.gov/pubmed/37346300
http://dx.doi.org/10.3389/fphar.2023.1170796
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spelling pubmed-102798472023-06-21 Dysfunction of von-Hippel Lindau factor causes reduced degradation of HIF leading to renal cancer. Hypoxia-inducible factor-prolyl hydroxylase enzyme inhibitors also lessen HIF destruction and could therefore increase renal cancer Waldum, Helge Front Pharmacol Pharmacology Frontiers Media S.A. 2023-06-06 /pmc/articles/PMC10279847/ /pubmed/37346300 http://dx.doi.org/10.3389/fphar.2023.1170796 Text en Copyright © 2023 Waldum. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Waldum, Helge
Dysfunction of von-Hippel Lindau factor causes reduced degradation of HIF leading to renal cancer. Hypoxia-inducible factor-prolyl hydroxylase enzyme inhibitors also lessen HIF destruction and could therefore increase renal cancer
title Dysfunction of von-Hippel Lindau factor causes reduced degradation of HIF leading to renal cancer. Hypoxia-inducible factor-prolyl hydroxylase enzyme inhibitors also lessen HIF destruction and could therefore increase renal cancer
title_full Dysfunction of von-Hippel Lindau factor causes reduced degradation of HIF leading to renal cancer. Hypoxia-inducible factor-prolyl hydroxylase enzyme inhibitors also lessen HIF destruction and could therefore increase renal cancer
title_fullStr Dysfunction of von-Hippel Lindau factor causes reduced degradation of HIF leading to renal cancer. Hypoxia-inducible factor-prolyl hydroxylase enzyme inhibitors also lessen HIF destruction and could therefore increase renal cancer
title_full_unstemmed Dysfunction of von-Hippel Lindau factor causes reduced degradation of HIF leading to renal cancer. Hypoxia-inducible factor-prolyl hydroxylase enzyme inhibitors also lessen HIF destruction and could therefore increase renal cancer
title_short Dysfunction of von-Hippel Lindau factor causes reduced degradation of HIF leading to renal cancer. Hypoxia-inducible factor-prolyl hydroxylase enzyme inhibitors also lessen HIF destruction and could therefore increase renal cancer
title_sort dysfunction of von-hippel lindau factor causes reduced degradation of hif leading to renal cancer. hypoxia-inducible factor-prolyl hydroxylase enzyme inhibitors also lessen hif destruction and could therefore increase renal cancer
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279847/
https://www.ncbi.nlm.nih.gov/pubmed/37346300
http://dx.doi.org/10.3389/fphar.2023.1170796
work_keys_str_mv AT waldumhelge dysfunctionofvonhippellindaufactorcausesreduceddegradationofhifleadingtorenalcancerhypoxiainduciblefactorprolylhydroxylaseenzymeinhibitorsalsolessenhifdestructionandcouldthereforeincreaserenalcancer

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