Disruption of the sialic acid/Siglec-9 axis improves antibody-mediated neutrophil cytotoxicity towards tumor cells

Upregulation of surface expressed sialoglycans on tumor cells is one of the mechanisms which promote tumor growth and progression. Specifically, the interactions of sialic acids with sialic acid-binding immunoglobulin-like lectins (Siglecs) on lymphoid or myeloid cells transmit inhibitory signals an...

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Detalles Bibliográficos
Autores principales: Lustig, Marta, Chan, Chilam, Jansen, J. H. Marco, Bräutigam, Maria, Kölling, Max A., Gehlert, Carina Lynn, Baumann, Niklas, Mester, Simone, Foss, Stian, Andersen, Jan Terje, Bastian, Lorenz, Sondermann, Peter, Peipp, Matthias, Burger, Renate, Leusen, Jeanette H. W., Valerius, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279866/
https://www.ncbi.nlm.nih.gov/pubmed/37346044
http://dx.doi.org/10.3389/fimmu.2023.1178817

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279866/
https://www.ncbi.nlm.nih.gov/pubmed/37346044
http://dx.doi.org/10.3389/fimmu.2023.1178817

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