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Clinical symptoms of SARS‐CoV‐2 breakthrough infection during the Omicron period in relation to baseline immune status and booster vaccination—A prospective multicentre cohort of health professionals (SURPRISE study)
The effects of different types of pre‐existing immunity on the frequency of clinical symptoms caused by the SARS‐CoV‐2 breakthrough infection were prospectively assessed in healthcare workers during the Omicron period. Among 518 participants, hybrid immunity was associated with symptom reduction for...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279996/ https://www.ncbi.nlm.nih.gov/pubmed/37346094 http://dx.doi.org/10.1111/irv.13167 |
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| author | Kohler, Philipp Babouee Flury, Baharak Güsewell, Sabine Egger, Thomas Leal, Onicio Brucher, Angela Lemmenmeier, Eva Meier Kleeb, Dorette Möller, J. Carsten Ortner, Manuela Rieder, Philip Ruetti, Markus Schmid, Hans‐Ruedi Stocker, Reto Vuichard‐Gysin, Danielle Speer, Oliver Wiggli, Benedikt Besold, Ulrike McGeer, Allison Risch, Lorenz Friedl, Andrée Schlegel, Matthias Vernazza, Pietro Kahlert, Christian R. Kuster, Stefan P. |
| author_facet | Kohler, Philipp Babouee Flury, Baharak Güsewell, Sabine Egger, Thomas Leal, Onicio Brucher, Angela Lemmenmeier, Eva Meier Kleeb, Dorette Möller, J. Carsten Ortner, Manuela Rieder, Philip Ruetti, Markus Schmid, Hans‐Ruedi Stocker, Reto Vuichard‐Gysin, Danielle Speer, Oliver Wiggli, Benedikt Besold, Ulrike McGeer, Allison Risch, Lorenz Friedl, Andrée Schlegel, Matthias Vernazza, Pietro Kahlert, Christian R. Kuster, Stefan P. |
| author_sort | Kohler, Philipp |
| collection | PubMed |
| description | The effects of different types of pre‐existing immunity on the frequency of clinical symptoms caused by the SARS‐CoV‐2 breakthrough infection were prospectively assessed in healthcare workers during the Omicron period. Among 518 participants, hybrid immunity was associated with symptom reduction for dizziness, muscle or limb pain and headache as compared to vaccination only. Moreover, the frequencies of dizziness, cough and muscle or limb pain were lower in participants who had received a booster vaccine dose. Thus, hybrid immunity appeared to be superior in preventing specific symptoms during breakthrough infection compared to vaccination alone. A booster vaccine dose conferred additional symptom reduction. |
| format | Online Article Text |
| id | pubmed-10279996 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2023 |
| publisher | John Wiley and Sons Inc. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-102799962023-06-21 Clinical symptoms of SARS‐CoV‐2 breakthrough infection during the Omicron period in relation to baseline immune status and booster vaccination—A prospective multicentre cohort of health professionals (SURPRISE study) Kohler, Philipp Babouee Flury, Baharak Güsewell, Sabine Egger, Thomas Leal, Onicio Brucher, Angela Lemmenmeier, Eva Meier Kleeb, Dorette Möller, J. Carsten Ortner, Manuela Rieder, Philip Ruetti, Markus Schmid, Hans‐Ruedi Stocker, Reto Vuichard‐Gysin, Danielle Speer, Oliver Wiggli, Benedikt Besold, Ulrike McGeer, Allison Risch, Lorenz Friedl, Andrée Schlegel, Matthias Vernazza, Pietro Kahlert, Christian R. Kuster, Stefan P. Influenza Other Respir Viruses Short Communications The effects of different types of pre‐existing immunity on the frequency of clinical symptoms caused by the SARS‐CoV‐2 breakthrough infection were prospectively assessed in healthcare workers during the Omicron period. Among 518 participants, hybrid immunity was associated with symptom reduction for dizziness, muscle or limb pain and headache as compared to vaccination only. Moreover, the frequencies of dizziness, cough and muscle or limb pain were lower in participants who had received a booster vaccine dose. Thus, hybrid immunity appeared to be superior in preventing specific symptoms during breakthrough infection compared to vaccination alone. A booster vaccine dose conferred additional symptom reduction. John Wiley and Sons Inc. 2023-06-19 /pmc/articles/PMC10279996/ /pubmed/37346094 http://dx.doi.org/10.1111/irv.13167 Text en © 2023 The Authors. Influenza and Other Respiratory Viruses published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Short Communications Kohler, Philipp Babouee Flury, Baharak Güsewell, Sabine Egger, Thomas Leal, Onicio Brucher, Angela Lemmenmeier, Eva Meier Kleeb, Dorette Möller, J. Carsten Ortner, Manuela Rieder, Philip Ruetti, Markus Schmid, Hans‐Ruedi Stocker, Reto Vuichard‐Gysin, Danielle Speer, Oliver Wiggli, Benedikt Besold, Ulrike McGeer, Allison Risch, Lorenz Friedl, Andrée Schlegel, Matthias Vernazza, Pietro Kahlert, Christian R. Kuster, Stefan P. Clinical symptoms of SARS‐CoV‐2 breakthrough infection during the Omicron period in relation to baseline immune status and booster vaccination—A prospective multicentre cohort of health professionals (SURPRISE study) |
| title | Clinical symptoms of SARS‐CoV‐2 breakthrough infection during the Omicron period in relation to baseline immune status and booster vaccination—A prospective multicentre cohort of health professionals (SURPRISE study) |
| title_full | Clinical symptoms of SARS‐CoV‐2 breakthrough infection during the Omicron period in relation to baseline immune status and booster vaccination—A prospective multicentre cohort of health professionals (SURPRISE study) |
| title_fullStr | Clinical symptoms of SARS‐CoV‐2 breakthrough infection during the Omicron period in relation to baseline immune status and booster vaccination—A prospective multicentre cohort of health professionals (SURPRISE study) |
| title_full_unstemmed | Clinical symptoms of SARS‐CoV‐2 breakthrough infection during the Omicron period in relation to baseline immune status and booster vaccination—A prospective multicentre cohort of health professionals (SURPRISE study) |
| title_short | Clinical symptoms of SARS‐CoV‐2 breakthrough infection during the Omicron period in relation to baseline immune status and booster vaccination—A prospective multicentre cohort of health professionals (SURPRISE study) |
| title_sort | clinical symptoms of sars‐cov‐2 breakthrough infection during the omicron period in relation to baseline immune status and booster vaccination—a prospective multicentre cohort of health professionals (surprise study) |
| topic | Short Communications |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279996/ https://www.ncbi.nlm.nih.gov/pubmed/37346094 http://dx.doi.org/10.1111/irv.13167 |
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