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Discovery of anti-SARS-CoV-2 secondary metabolites from the heartwood of Pterocarpus santalinus using multi-informative molecular networking

A pigment-depleted extract from the heartwood of Pterocarpus santalinus L. f. (PS-DE) showed promising anti-SARS-CoV-2 activity with an IC(50) of 29.9 μg/mL in Caco-2-F03 cells. To determine the potential active constituents within the extract prior to isolation, multi-informative molecular network...

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Detalles Bibliográficos
Autores principales:	Wasilewicz, Andreas, Zwirchmayr, Julia, Kirchweger, Benjamin, Bojkova, Denisa, Cinatl, Jindrich, Rabenau, Holger F., Rollinger, Judith M., Beniddir, Mehdi A., Grienke, Ulrike
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10280016/ https://www.ncbi.nlm.nih.gov/pubmed/37347040 http://dx.doi.org/10.3389/fmolb.2023.1202394

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